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Clinical trials news

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The search for a cure
NIH study supports use of short-term HIV treatment interruption in clinical trials

A short-term pause in HIV treatment during a carefully monitored clinical trial does not lead to lasting expansion of the HIV reservoir nor cause irreversible damage to the immune system, new findings suggest.

Published
11 January 2018
From
National Institutes of Health
Clinical trials
Setting the Standard: New prevention trials in the era of oral PrEP

There’s a lot going on in the world of HIV prevention research right now. One key issue is how participants might access oral PrEP as part of HIV prevention trials. It may seem simple: trial participants have the right to the highest standard of HIV prevention and care as part of participation. But the ethics, trial design issues and the mechanisms by which interventions are provided as standard of care are quite complex. Opinions differ and politics abound.

Published
08 December 2017
From
AVAC
The search for a cure
European Cure Review concentrates on HIV therapeutic vaccines

A cure for HIV would almost inevitably have to involve a vaccine to improve the body’s natural ability to control HIV, a seminar on European HIV cure

Published
16 November 2017
By
Gus Cairns
PrEP
High HIV incidence from non-primary partners and low PEP and PrEP use seen in PARTNER study

HIV incidence among the HIV-negative gay men in the PARTNER 1 and 2 studies, due to sex with partners outside the main relationship, was high,

Published
08 November 2017
By
Gus Cairns
Cancer
For cancer patients with HIV, immunotherapy appears safe

Checkpoint inhibitor study suggests new treatment options for patients long excluded from cancer immunotherapy clinical trials

Published
08 November 2017
From
Fred Hutch
Microbicides
DAIDS Boss Muses on the Future of HIV Prevention Research

Below are some of Dr. Dieffenbach’s rather intentionally provocative ideas about specific HIV prevention research candidates—challenges and promises, and the questions they may raise for the next clinical trial research network structure.

Published
20 October 2017
From
AVAC
PrEP
PrEP activists warn new NHS trial will fail if black gay men don't take part

Sexual health campaigners are warning a newly launched trial in the UK will fail if not enough people of color take part, Gay Star News can reveal. The experts are estimating the overwhelming majority of the patients in the NHS trial will be white gay men. This could provide an unbalanced study with most of the evidence from just one group who could benefit from access to PrEP.

Published
13 October 2017
From
Gay Star News
PrEP
England PrEP Impact Trial Launches

The England PrEP IMPACT Trial goes live tomorrow. Before you all go rushing out to your local sexual health clinic there are a few things we’d like to make you aware of. The trial team are expecting an initial surge for demand and clinics are doing their best to accommodate this. There are a few things we can do to help. Please try to wait until your regular clinic opens as part of the trial rather than register at a new clinic - though we completely understand that expecting people to wait for access to NHS PrEP is unacceptable to some. The trial team are pushing really hard for most of the 70 initial sites to be live as soon as possible with the remaining 130 clinics following quickly behind. Most clinics are expected to be up by the end of November and all by April 2018.

Published
11 October 2017
From
I Want PrEP Now
Clinical trials
PrEP presents questions for HIV prevention researchers, survey seeks answers

In any trial of an HIV prevention measure, ethics demand that all known effective measures, which in earlier years added up to counseling and condoms, be made available. In a setting where PrEP would not otherwise be available though, is offering it sweetening the pot more than is ethically acceptable?

Published
04 October 2017
From
Science Speaks
PrEP
5 things you need to know to join the IMPACT trial

The PrEP IMPACT trial is a clinical trial in England and will operate differently to the ways you usually get sexual health services. You'll need to meet eligibility criteria to go on the trial, and you'll need to read and sign paperwork before you start. You'll also be asked to visit your trial clinic every 3 months for HIV and STI tests. The PrEP IMPACT trial starts in September 2017 – and there are 5 important sets of things you need to know if you’re thinking about joining the trial.

Published
07 September 2017
From
PrEPster
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Community Consensus Statement on Access to HIV Treatment and its Use for Prevention

Together, we can make it happen

We can end HIV soon if people have equal access to HIV drugs as treatment and as PrEP, and have free choice over whether to take them.

Launched today, the Community Consensus Statement is a basic set of principles aimed at making sure that happens.

The Community Consensus Statement is a joint initiative of AVAC, EATG, MSMGF, GNP+, HIV i-Base, the International HIV/AIDS Alliance, ITPC and NAM/aidsmap
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This content was checked for accuracy at the time it was written. It may have been superseded by more recent developments. NAM recommends checking whether this is the most current information when making decisions that may affect your health.

NAM’s information is intended to support, rather than replace, consultation with a healthcare professional. Talk to your doctor or another member of your healthcare team for advice tailored to your situation.